Oral inhalation is well recognized as an efficient method of drug delivery by many pharmaceutical companies, driving the continuing development of branded as well as generic dry powder inhalers (DPIs). However, the complexities of developing a DPI-suitable formulation are not straightforward; there are several often contradictory requirements these formulations must conform to.
Accurate and dependable equipment is the foundation for a perfect laboratory. Hosokawa believes there are key ingredients critical to this recipe – precision analysis tools and reliable processing systems. On Thursday, March 22nd at 2:00 PM (Eastern Time), Hosokawa will host a webinar focusing on these important laboratory devices.
This article explains the basics of dry powder classification and describes some of the most common classification methods available for bulk solids manufacturing applications.
Carbon Black is a material produced from the incomplete combustion of hydrocarbons and is an essential component in tires, rubber, plastics and liquids, enhancing these products by adding strength and durability. Most Carbon Black is produced in an atmosphere controlled furnace where fuel is introduced into a hot gas stream that produces sufficient heat to vaporize and pyrolyze the fuel into ultra-fine carbon particles. At this point the carbon black is an inconsistent mixture of fine particles and agglomerates referred to as grit. These grit particles are an unwanted byproduct, and can adversely affect the physical properties of the rubber and plastic products.
With the capability of on-site OEL testing services Hosokawa can offer an improved, single source supply of containment solutions to drug manufacturers seeking solutions for the safe handling of potentially harmful or high toxicity materials and for processors in other industries keen to meet the increasing obligations regarding personnel safety and product security.
When specialty fabric manufacturer Vlisco approached HML seeking a contained drum handling solution to provide a physical barrier between the operator and product to protect their workforce from contact with airborne, fabric dye particles, they were explicit in the challenges that needed to be met.
Drying specialist Hosokawa Micron B.V. offer competitive edge drying technologies and processing options for the production of complex pharmaceutical products.
In response to increasing market demand for high temperature powder processing Hosokawa Micron B.V. has developed a range of new technologies that address the requirement for processing temperatures up to 325°C.
Nauta Conical Screw Mixers are among the most popular homogenizers for blending powdered materials. Since Hosokawa invented the Nauta Mixer in 1946, over 15,000 blenders have been built, from 5 liter small batch mixers to large productionblenders with 120,000 liter capacity. The Nauta mixers are also available with many options and specialized configurations for vacuum drying, low and high shear mixing, and lyophilization.
Over the last 90 years, Hosokawa has conducted processing trials on thousands of food ingredients and installed hundreds of systems – everything from ultra-fine milling of sugar and blending large batches of dry ingredients, to vacuum drying and sterilization of delicate spices. Rob Voorhees, President of Hosokawa Micron Powder Systems, will be conducting a webinar focusing on processing seven common food materials on Wednesday, August 9th at 2:00 PM.